In February 2018 researchers from New Zealand published the results of their study to assess whether fructose present in fruit is of sufficient quantity or in a form that is able to increase the uric acid concentration in the blood. 73 individuals were divided into three groups: one group to consume small (205 g) and large (410 g) servings of apple segments, the second to consume small (170 mL) and large (340 mL) servings of apple juice, and the third a glucose and a fructose control beverage. The fructose control beverage and the large servings of apple and apple juice contained 26.7g fructose. Blood samples were taken at the beginning of the study and at 30 and 60 minutes after intake. Results showed that the uric acid concentrations in the blood increased after the intake of all fructose-containing samples and decreased after the glucose beverage. Blood pressure taken 70 min after intake was unaffected. There was no difference in change in satiety between the fructose and glucose control beverages, but the individuals felt more full 30 min after ingesting the whole apple than after apple juice.
White SJ et al. The effects of apples and apple juice on acute plasma uric acid concentration: a randomized controlled trial. Am J Clin Nutr. 2018 Feb 1;107(2):165-172